| Primary Identifier | MGI:5636684 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ndrg2 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 4. Cre-mediated recombination removed the selection cassette along with exons 3 and 4. RT-PCR and Western blot analysis confirmed absence of mRNA and protein expression in the brain, liver, and heart from homozygous mutant mice. |
