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Allele : Ndrg2<tm1.1Hori> N-myc downstream regulated gene 2; targeted mutation 1.1, Osamu Hori

Primary Identifier  MGI:5636684 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ndrg2
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 4. Cre-mediated recombination removed the selection cassette along with exons 3 and 4. RT-PCR and Western blot analysis confirmed absence of mRNA and protein expression in the brain, liver, and heart from homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ndrg2<->,
  • Ndrg2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele