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Allele : Dvl2<tm1.1Wds> dishevelled segment polarity protein 2; targeted mutation 1.1, William D Snider

Primary Identifier	MGI:5659941	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Dvl2
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false

molecularNote

An FRT flanked neo cassette and loxP site were inserted upstream of exon 2 and a loxP site was inserted into exon 15 distal to the stop codon. Flp mediated recombination removed the neo cassette.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Dvl2<flox>,
Dvl2<tm2.1Awb>,
Dvl2<flox>,
Dvl2<tm2.1Awb>

earliestPublication:
Ohata S, et al. (2014) Loss of Dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus. Neuron 83(3):558-71

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

5 Publication categories

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