Primary Identifier | MGI:5661839 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence, Null/knockout | Gene | Comt |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct was designed to replace the entire endogenous coding region with the human sequence following by a neomycin (neo) resistance cassette. Western blot analysis confirmed the absence of protein expression in the hippocampus and cortex. |