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Allele : Comt<tm1(COMT)Xzho> catechol-O-methyltransferase; targeted mutation 1, Xianjin Zhou

Primary Identifier  MGI:5661839 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Null/knockout Gene  Comt
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct was designed to replace the entire endogenous coding region with the human sequence following by a neomycin (neo) resistance cassette. Western blot analysis confirmed the absence of protein expression in the hippocampus and cortex.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Human COMT Val,
  • Human COMT Val
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele