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Allele : Fancb<em1Shnk> Fanconi anemia, complementation group B; endonuclease-mediated mutation 1, Satoshi H Namekawa

Primary Identifier  MGI:5688399 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Fancb
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
description  Lines 164, 167, 171 and 84 were generated in the same experiment. However, lines 164, 167 and 171 were all infertile males. J:224588
molecularNote  Zinc finger nuclease technology was used to modify exon 2 by deleting CAGTT. This mutation results in a premature stop codon and truncation at amino acid 307 of 853. Western blot analysis confirmed the absence of protein in testes. The allele was isolated in line 84.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories