| Primary Identifier | MGI:5702632 | Allele Type | Targeted |
| Attribute String | Hypomorph | Gene | Gas7 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin resistance cassette with a loxP site and stop codons was inserted into exon 6b. Western blot analysis confirmed the absence of full-length protein and low level expression of a truncated protein. A protein degradation assay revealed that the expressed mutant protein is more easily degraded than the wild-type in primary cortical cultured neurons from E16.5 wild-type and homozygous mutant mice. |
