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Allele : Ripk1<tm1.2Pvdb> receptor (TNFRSF)-interacting serine-threonine kinase 1; targeted mutation 1.2, Peter Vandenabeele

Primary Identifier  MGI:5749417 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ripk1
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 3 floxed. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories