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Allele : Ripk1<tm1.1Gsk> receptor (TNFRSF)-interacting serine-threonine kinase 1; targeted mutation 1.1, GlaxoSmithKline

Primary Identifier  MGI:5749467 Allele Type  Targeted
Gene  Ripk1 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 3 was replaced with a modified one in which a point mutation results in the amino acid substitution of alanine for lysine at position 45 (K45A). Flp-mediated recombination removed the FRT flanked neomycin resistance cassette with a 3' loxP site inserted downstream of the modified exon 3.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Ripk1<K45A>,
  • Ripk1<K45A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

27 Publication categories