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Allele : Klf2<tm1.1Hhn> Kruppel-like transcription factor 2 (lung); targeted mutation 1.1, Huck Hui Ng

Primary Identifier  MGI:5750068 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Klf2
Transmission  Germline Strain of Origin  (C57BL/6J x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The L1L2_Bact_P cassette was inserted at a position on Chromosome 8, resulting in a 1594bp deletion starting at position 72319391 and ending at position 72320985, including exons 2 and 3 of the Klf2 gene. The targeting vector is composed of an FRT site followed by En2SA (mouse engrailed 2 gene splice acceptor), IRES-lacZ sequence, a loxP site, a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Cre-mediated recombination removed the floxed neomycin cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories