| Primary Identifier | MGI:5751213 | Allele Type | Targeted |
| Attribute String | Constitutively active, Inserted expressed sequence | Gene | Vav2 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting contruct introduced downstream of exon 1 a floxed STOP and neomycin resistance cassette, three hemagglutinin (HA) tags, a truncated Vav2 cDNA (delta1-184) and a human growth hormone polyadenylation sequence. This truncated version is phosphorylation-independent and has constitutitive exchange activity due to the removal of the N-terminal inhibitory domains. Cre-mediated recombination removed the STOP/selection cassette. |
