| Help | About | Contact Us

Allele : Nlrp6<tm1Opaz> NLR family, pyrin domain containing 6; targeted mutation 1, Nelson Ruiz-Opazo

Primary Identifier	MGI:5752293	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Nlrp6
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

An 800 bp region containing the 3' end of exon 4 plus part of the 5' end of intron 4 was replaced with a pgk-neo cassette via homologous recombination. RT-PCR analysis confirmed the absence of intact mRNA in kidneys from homozygous mutant mice.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
AVR/NAVR<->,
AVR/NAVR<->

earliestPublication:
Herrera VL, et al. (2011) AVR/NAVR deficiency lowers blood pressure and differentially affects urinary concentrating ability, cognition, and anxiety-like behavior in male and female mice. Physiol Genomics 43(1):32-42

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

4 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76574288

MouseMine