Primary Identifier | MGI:5753066 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd84 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette replaced the splice donor site of exon 1, the complete intron 1, and a critical part of exon 2 (comprising parts of the 5' UTR, the translation initiation site and the coding sequence of the signal peptide). Western blot analysis and flow cytometry confirmed the absence of protein expression in platelets. |