| Primary Identifier | MGI:5754367 | Allele Type | Targeted |
| Attribute String | Modified isoform(s) | Gene | Chn1 |
| Transmission | Germline | Strain of Origin | C57BL/6NSlc |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upsteam of exon 7. An additional loxP site was inserted into the untranslated region of exon 7. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the untranslated region in exon 7. Western blot analysis confirmed the absence of alpha1 isoform expression but continued expression of isoform alpha2 in the hippocampus. |
