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Allele : Eef2k<tm1.1Cgpd> eukaryotic elongation factor-2 kinase; targeted mutation 1.1, Christopher G Proud

Primary Identifier	MGI:5759976	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Eef2k
Transmission	Germline	Strain of Origin	C57BL/6
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 7. An FRT-flanked neomycin resistance cassette with a 3'loxP site was inserted downstream of exon 10. Cre-mediated recombination removed exons 7 through 10 along with the selection cassette. (pers comm)

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Moore CE, et al. (2015) Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia. Mol Cell Biol 35(10):1788-804

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

9 Publication categories

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