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Allele : Folh1<tm2Nle> folate hydrolase 1; targeted mutation 2, Joseph H Neale

Primary Identifier  MGI:5766053 Allele Type  Targeted
Attribute String  Null/knockout Gene  Folh1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced exon 3 through 5. Western blot analysis confirmed the absence of protein expression in the brain of homozygous mutant mice. The residual N-acetylaspartylglutamate (NAAG) hydrolyzing activity in the brain was ~6% of that seen in wild-type controls.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • GCPII<->,
  • GCPII KO,
  • GCPII<->,
  • GCPII KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories