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Allele : Tlr4<tm1.2Karp> toll-like receptor 4; targeted mutation 1.2, Christopher Karp

Primary Identifier  MGI:5776718 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tlr4
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector containing a FRT site flanked neomycin selection cassette and a loxP site was inserted downstream of exon 3 of the targeted gene, and another loxP site was inserted upstream of exon 3. Flp-mediated recombination removed the FRT-flanked neo cassette. Cre-mediated recombination removed exon 3.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

67 Publication categories