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Allele : Nlk<tm2c(KOMP)Wtsi> nemo like kinase; targeted mutation 2c, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5788454 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Nlk
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The L1L2_Bact_P cassette was inserted at position 78517165 of Chromosome 11 upstream of exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 2 at position 78518021. Exon 2 thus flanked by loxP sites. Flp-mediated recombination removed the FRT-flanked lacZ sequence and neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Nlk-loxP,
  • Nlk-loxP
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories