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Allele : Sgta<tm1.1Drmcr> small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha; targeted mutation 1.1, Dame Roma Mitchell Cancer Research

Primary Identifier  MGI:5788683 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sgta
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a loxP upstream of exon 4 (containing the start codon), and an FRT-flanked neomycin resistance (neo) cassette, followed by a second loxP site, downstream of exon 5 gene. Cre-mediated recombination removed exons 4 through 5 and the neo cassette. Western blot and immunohistochemistry of prostrate and ovary confirmed that no protein was expressed in mutant mice.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories