Primary Identifier | MGI:5810960 | Allele Type | Endonuclease-mediated |
Gene | Cdc14a | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | CRISPR/Cas-9 technology was used to generate a single point mutation (c.832T>A) which results in a serine to cysteine substitution at codon-278 (p.C278S) that ablates phosphatase catalytic activity while maintaining overall protein tertiary structure. |