|  Help  |  About  |  Contact Us

Allele : Cdc14a<em1Tbf> CDC14 cell division cycle 14A; endonuclease-mediated mutation 1, Thomas B Friedman

Primary Identifier  MGI:5810960 Allele Type  Endonuclease-mediated
Gene  Cdc14a Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas-9 technology was used to generate a single point mutation (c.832T>A) which results in a serine to cysteine substitution at codon-278 (p.C278S) that ablates phosphatase catalytic activity while maintaining overall protein tertiary structure.
  • mutations:
  • Single point mutation
  • synonyms:
  • C278S-CDC14A,
  • C278S-CDC14A
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele