Primary Identifier | MGI:5816976 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Il23r |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The proximal loxP site was inserted together with a neomycin selection cassette flanked by FRT sites within intron 3 of the Il23r gene, the distal loxP site was introduced within intron 4. The resultant mouse line was bred to a FLP deleter-line, which ubiquitously expresses Flp-recombinase to excise the neomycin selection cassette. |