|  Help  |  About  |  Contact Us

Allele : Marchf8<tm1.1Lkle> membrane associated ring-CH-type finger 8; targeted mutation 1.1 Ludger Klein

Primary Identifier  MGI:5819100 Allele Type  Targeted
Attribute String  Null/knockout Gene  Marchf8
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP flanked neomycin selection cassette replaced exons 5 and 6, which encode the catalytically active site in the RING variant (RINGv) domain and the TM domain, respectively. Mice carrying tjhe targeted allele were mated to a CAG-Cre deleter mouse line to remove the neomycin cassette in the final allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories