| Primary Identifier | MGI:5882517 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Cpne6 |
| Transmission | Germline | Strain of Origin | C57BL/6 x 129 |
| Is Recombinase | false | Is Wild Type | false |
| description | The embryonic stem cells used in the original reference (J:239922) were "75% C57BL/6, 25% 129Sv". |
| molecularNote | The entire complement of coding exons 2-16 was replaced with an nls-lacZ reporter gene cassette and a loxP-flanked neomycin resistance gene cassette. Subsequently, the neo cassette was removed through cre-mediated recombination, leaving a reporter and null allele. Western blot analysis of hippocampal lysates confirmed the absence of protein expression in homozygous mutant mice. |
