| Primary Identifier | MGI:5882518 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Krt36 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| description | Crossing these mice to animals expressing Cre recombinase is not recommended because Cre-mediated recombination results in production of a hybrid keratin mRNA (presumably involving another, closely linked keratin gene), a partially functional protein, and a milder homozygous (hypomorphic) phenotype. (J:82809) |
| molecularNote | A loxP-flanked neomycin selection cassette has replaced exons 1-3. No Krt36 mRNA is detectable in homozygous mutant mice retaining the cassette. |
