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Allele : Uhrf1<tm1c(EUCOMM)Wtsi> ubiquitin-like, containing PHD and RING finger domains, 1; targeted mutation 1c, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5888866 Allele Type  Targeted
Attribute String  Conditional ready Gene  Uhrf1
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_gt0 cassette was inserted at position 56617252 of Chromosome 17 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 56618186. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele to remove the lacZ sequence and neo selection cassette, leaving loxP sites flanking the critical exon(s).
  • mutations:
  • Insertion
  • synonyms:
  • Uhrf1<fl>,
  • Uhrf1<fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories