| Primary Identifier | MGI:7779621 | Allele Type | Endonuclease-mediated |
| Gene | Spocd1 | Strain of Origin | (C57BL/6J x CBA/CaCrl)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a mutation of eight amino acids to alanine (GIRLVGAASS to AAAAAAAAA) in exon 4 in the predicted beta-hairpin that mediates SPIN1 binding. This generates a separation-of-function allele that encodes a SPOCD1 variant that no longer interacts with SPIN1. |
