Primary Identifier | MGI:5904667 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Wnt10a |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
description | Phenotypic Similarity to Human Syndrome: WNT10A mutation |
molecularNote | LoxP sites were inserted flanking exons 3 and 4, which encode 20 of the 24 conserved, functionally required cysteine residues. Mice carrying this allele were crossed with CMV-Cre mice to delete the loxP-flanked region. |