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Allele : Orai2<tm1.1(KOMP)Vlcg> ORAI calcium release-activated calcium modulator 2; targeted mutation 1.1, Velocigene

Primary Identifier  MGI:5908178 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Orai2
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-Regeneron
molecularNote  The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 11345bp between positions 136626234-136637578 of Chromosome 5 (Genome Build37), deleting virtually the entire coding region (located on exons 2 and 3). The cassette contains a lacZ reporter gene cassette and a loxP site flanked neomycin resistance gene cassette. The neo gene was removed through subsequent cre-mediated recombination. The absence of transcription and translation from this allele was confirmed by qRT-PCR and immunoblots.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Orai2<LacZ>,
  • Orai2<LacZ>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

5 Publication categories