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Allele : Mcm3<tm1.1Geno> minichromosome maintenance complex component 3; targeted mutation 1.1, Genoway

Primary Identifier  MGI:5907491 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph, Reporter Gene  Mcm3
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted in intron 13 and IRES-EGFP-Luciferase cassette, FRT flanked neo cassette and loxP site were inserted after the stop codon in exon 17. Flp mediated recombination removed the neo cassette. In heterozygous and homozygous MEFs, mRNA expression is reduced to about 70% and 30% of wild-type levels.
  • mutations:
  • Insertion
  • synonyms:
  • Mcm3<Lox>,
  • Mcm3<Lox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories