Primary Identifier | MGI:6121067 | Allele Type | Spontaneous |
Attribute String | Null/knockout | Gene | Strip1 |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The mutation is a three nucleotide (CTG) in-frame deletion in exon 16. This mutation is predicted to result in the deletion of a leucine residue in a highly conserved stretch of five leucines (amino acids 537541) of the encoded protein. In vitro studies showed that the mutant protein is unstable and is present at 1% of the control level. |