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Allele : Ptpro<tm1.1Ael> protein tyrosine phosphatase receptor type O; targeted mutation 1.1, Ari Elson
Primary Identifier  MGI:6112577 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Ptpro
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The P2 distal promoter that regulates expression of isoform t was deleted. Expression via the proximal P1 promoter of the gene is unaffected, hence these mice produce the mRNA and protein of the distinct GLEPP-1. Cre-mediated recombination removed the neomycin resistance cassette inserted upstream of exon S1.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • ROKO,
  • ROKO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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