| Primary Identifier | MGI:6104259 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Mep1b |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GTGTGTCCCCCCACTGAAAA, ACAGGGTGTTTGCCTCACTG, GAGTATTTAGAGAAGATACC and GCAATCAGTTGTCCAATAAC, which resulted in a 425 bp deletion beginning at Chromosome 18 positive strand position 21,086,087 bp and ending after 21,086,511 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000276519 (exon 7) and 246 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 124 and early truncation 9 amino acids later. |
