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Allele : Acer3<tm1Cmao> alkaline ceramidase 3; targeted mutation 1, Cungui Mao
Primary Identifier  MGI:6115367 Allele Type  Targeted
Attribute String  Hypomorph Gene  Acer3
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector containing a neomycin resistance (neo) cassette was used to replace exon 8. Analysis by RT-PCR reveals that a truncated coding sequence is transcribed. Catalytic activity of ACER3 is markedly decreased, but not completely abolished.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

7 Publication categories





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