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Allele : Asic4<tm1.1(cre/ERT2)Cibms> acid-sensing ion channel family member 4; targeted mutation 1.1, Chih-Cheng Chen

Primary Identifier  MGI:6120518 Allele Type  Targeted
Attribute String  Inducible, Null/knockout, Recombinase Gene  Asic4
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  Thetargeting vector was constructed with the cre/ERT2 gene knocked into the initiator methionine of mouse ASIC4 to replace first 267 amino acid peptides in the N-terminus of ASIC4. A pGK-neo selection cassette flanked by loxP sites was placed downstream of the polyadenylation signal of cre/ERT2. The floxed-pGK-neo cassette was removed by crossing with cre expressing mice. It is a null allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Asic4<->,
  • Asic4<CreERT2>,
  • ASIC4-KO/CreERT2,
  • Asic4<CreERT2>,
  • ASIC4-KO/CreERT2,
  • Asic4<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

3 Publication categories