Primary Identifier | MGI:6120518 | Allele Type | Targeted |
Attribute String | Inducible, Null/knockout, Recombinase | Gene | Asic4 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | Thetargeting vector was constructed with the cre/ERT2 gene knocked into the initiator methionine of mouse ASIC4 to replace first 267 amino acid peptides in the N-terminus of ASIC4. A pGK-neo selection cassette flanked by loxP sites was placed downstream of the polyadenylation signal of cre/ERT2. The floxed-pGK-neo cassette was removed by crossing with cre expressing mice. It is a null allele. |