| Primary Identifier | MGI:6120740 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Fbxo7 |
| Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | EUCOMM |
| description | In J:272313, mice carrying the Fbxo7tm1b(EUCOMM)Wtsi allele (whereby the critical exon was deleted by Cre recombinase) were generated by treating Fbxo7tm1a(EUCOMM)Wtsi two-cell embryos with cell permeable Cre as reported in J:213544. |
| molecularNote | Cre-mediated excision of the parental Fbxo7tm1a(EUCOMM)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon 4 leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. |
