Primary Identifier | MGI:6148207 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Per2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Cre-mediated recombination of loxP sites that flanked exon 6 resulted in the deletion of this exon. The deletion leads to a truncated PER2 protein consisting of the first 188 N-terminal amino acids (out of 1,257) plus 23 unrelated amino acids containing no structural elements involved in interaction with other clock proteins. |