| Primary Identifier | MGI:6150887 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Rnf146 |
| Transmission | Germline | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| description | Mice homozygous for the Rnf146tm1.1Rtpl allele and hemizygous for the Tg(Sp7-tTA,tetO-EGFP/cre)1Amc transgene exhibit a Cleidocranial dysplasia (CCD)-like syndrome J:244583). Phenotypic Similarity to Human Syndrome: cleidocranial dysplasia (DOID:13994). |
| molecularNote | A loxP site was inserted into intron 3. A second loxP site was inserted into the 3' UTR of exon 4. Flp-mediated recombination removed the FRT-flanked selection cassette inserted into the 3' UTR. |
