| Primary Identifier | MGI:6149967 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Ttc7 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GCACCCACCCACTCAAACCA, ATAAACCTAAATCGTCTCTG, CATGGGGCTAAAAAGTACCT and CCAGTGGATAGCAGAAGCTA, which resulted in a 665 bp deletion beginning at Chromosome 17 position 87,289,963 bp and ending after 87,290,627 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001000115 (exon 2) and 501 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 62 and early truncation 5 amino acids later. |
