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Allele : Trim13<em1(IMPC)Tcp> tripartite motif-containing 13; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6156472 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Trim13
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR1020 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GGAATGTGCGGAATTCCCTG targeting the 5' side and AGTTATGCAAACCTATGACC targeting the 3' side of a critical exon. This resulted in a 511-bp deletion Chr14:61604671 to 61605181; p.L46Tfs*45 resulting in a frameshift mutation in all annotated full length protein-coding transcripts (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

5 Publication categories