| Primary Identifier | MGI:6156896 | Allele Type | Targeted |
| Attribute String | Constitutively active | Gene | Becn1 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A floxed neo cassette was inserted in intron 7 and an F121A mutation was created in exon 6 via homologous recombination. Cre-meditated recombination removed the neo cassette. The mutation in exon 6 disrupts binding to BCL2 resulting in constitutively high autophagy. |
