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Allele : Me1<em1(IMPC)Tcp> malic enzyme 1, NADP(+)-dependent, cytosolic; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6156600 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Me1
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR0861 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of CCGCCCTTGTTGTGCACAAA and CCTGTAATGCAGAGTATGTA targeting the 5' side and GTCTAACTGGAGAGTATCAT and GGCATGCAGCTCTAGGTTGT targeting the 3' side. This resulted in a 974-bp deletion from Chr9: 86619475 to 86620448 (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

5 Publication categories