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Allele : Ccdc8<em2(IMPC)Tcp> coiled-coil domain containing 8; endonuclease-mediated mutation 2, The Centre for Phenogenomics

Primary Identifier  MGI:6157332 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ccdc8
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR0586 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of CCAGCCAGGCGGACCTCCCG and GATACGGGCCACATCTTCCA targeting the 5' side and CCAGGAGCCTCCGGGTACTA and TCCCAGTAGCTAACAAAGGC targeting the 3' side of exon ENSMUSE00000599706 resulting in a 121-bp deletion of Chr7 from 16994632 to 16994752, and c.197delC (22-bp downstream of gRNA_U3).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories