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Allele : Ripk1<tm1.1Mkel> receptor (TNFRSF)-interacting serine-threonine kinase 1; targeted mutation 1.1, Michelle Kelliher
Primary Identifier  MGI:6272324 Allele Type  Targeted
Gene  Ripk1 Transmission  Germline
Strain of Origin  B6.Cg-Thy1<a> Is Recombinase  false
Is Wild Type  false
molecularNote  A floxed neo cassette was inserted into intron 3 and a mutation was introduced in exon 4 creating an aspartate to aspargine substitution at position 138 (p.D138N). Cre mediated recombination removed the neo cassette. This mutation alters kinase activity of the protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Ripk1<D138N>,
  • Ripk1<D138N>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

28 Publication categories





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