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Allele : Fto<em1Fmas> FTO alpha-ketoglutarate dependent dioxygenase; endonuclease-mediated mutation 1, Frances M Ashcroft
Primary Identifier  MGI:6159866 Allele Type  Endonuclease-mediated
Gene  Fto Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  A CGT -> GCT (R313A) mutation was created in exon 5 via CRISPR/Cas9 meidated recombination. This mutation is designed be orthologus to a human mutation that eliminates demethylase activity.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • FTO-R313A,
  • FTO-R313A
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories





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