| Primary Identifier | MGI:6188008 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Kpna4 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 4 guide sequences TTGGTAGAAAATAAACTACC, AAACATTTCACATACTAGAG, GTATGTTACTTTACAAATCT and ACATTTCTAAGTCAGGATGT, which resulted in a 293 bp deletion beginning at Chromosome 3 position 69,094,589 bp and ending after 69,094,881 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000567751 (exon 7) and 207 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 127 and early truncation 18 amino acids later. |
