Primary Identifier | MGI:6200322 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Ikzf1 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced C to A transversion at base pair 11,748,464 (v38) on chromosome 11, or base pair 63,496 in the GenBank genomic region NC_000077 encoding Ikzf1. The mutation corresponds to residue 872 in the mRNA sequence NM_001025597 within exon 4 of 8 total exons. The mutation results in substitution of serine 105 for a premature stop codon (S105*) in variant 1 of the IKZF1 protein. |