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Allele : Daxx<tm2.1Led> Fas death domain-associated protein; targeted mutation 2.1, Philip Leder

Primary Identifier  MGI:6256965 Allele Type  Targeted
Attribute String  Null/knockout Gene  Daxx
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A FRT site flanked targeting vector, with a loxP site at the downstream end and containing a PGK-neo selection cassette was utilized in the construction of this mutant. This selection cassette was inserted downstream of exon I (also called exon 2, when the first non-coding exon is included in the numbering scheme) of the targeted gene, and another loxP site was inserted upstream of exon III (also called exon 4, when the first non-coding exon is included in the numbering scheme). The PGK-neo selection cassette was removed by Flp-recombinase mediated excision. Exon II is flanked by loxP sites. Cre-mediated recombination removed exon II.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Daxx<delta3>,
  • Daxx<&Delta;3>,
  • Daxx<&Delta;3>,
  • Daxx<delta3>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele