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Allele : Plek2<em1(IMPC)Tcp> pleckstrin 2; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6274931 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Plek2
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele from project TCPR1235 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of ATCCTCTAATTGGACACCTT and CTGACTACCTATGAGTGCAA targeting the 5' side and GCACTCTGTCTTAAGCGGAA and GTAATGGTCACCTGTTTGGT targeting the 3' side of a critical region. This resulted in a 1141-bp del Chr12:78895781 to 78896921 (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories